Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorSichuan Provincial People's Hospital
About this trial
This is a single-center prospective observational study designed to evaluate the effectiveness of multimodal muscle ultrasound for the assessment of sarcopenia in kidney transplant recipients. Adult patients undergoing kidney transplantation will undergo both muscle ultrasound and bioelectrical impedance analysis (BIA) at predefined time points before and after transplantation.
The primary objective is to evaluate the diagnostic performance of muscle ultrasound for sarcopenia assessment, including its correlation and agreement with BIA-derived skeletal muscle index (BIA-SMI), as well as its diagnostic accuracy. Secondary objectives include describing the longitudinal changes in sarcopenia prevalence and muscle-related parameters from the pre-transplant period to 1 year after transplantation.
The study aims to provide evidence for a convenient, noninvasive, radiation-free, and reliable method for sarcopenia assessment in kidney transplant recipients.
Eligibility criteria
Qualifiers
Adult patients aged 18 years or older
Patients scheduled to undergo kidney transplantation
Ability to undergo muscle ultrasound and bioelectrical impedance analysis (BIA)
Ability to provide written informed consent
Disqualifiers
Patients with severe limb deformity or conditions preventing muscle ultrasound assessment
Patients with implanted electronic devices contraindicating BIA assessment
Inability to complete study assessments
Trial design
Treatments tested in this trial
- Muscle Ultrasound
Treatment groups
140 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov