Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIstituti Clinici Scientifici Maugeri SpA
About this trial
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are:
* to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress.
Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.
Eligibility criteria
Qualifiers
Age > 18 years
Post-stroke aphasia
Post-stroke neglect
Patients with disorders of consciusness (DOC)
Disqualifiers
No auditory injury
no hystory of neurological disease
No hystory of psychiatric disease
Previous stroke
Trial design
Treatments tested in this trial
- Combinatory effect of music stimulation and neurostimulation
Treatment groups
90 Participants
are divided into 3 treatment groupsSponsors and collaborators
Istituti Clinici Scientifici Maugeri SpA
Lead sponsor
University of Bari Aldo Moro
Collaborator
University of Aarhus
Collaborator
Source ClinicalTrials.gov