The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength. It will also explore whether this treatment can help slow down muscle weakening.
The main questions this study aims to answer are:
* Do participants develop medical problems when receiving electrical muscle stimulation in the ICU? * Is electrical muscle stimulation a practical way to help reduce muscle weakness in critically ill patients?
Researchers will compare the control group (standard of care) to the intervention group (standard of care plus 60-minute sessions of electrical muscle stimulation daily during the ICU stay) to see if the device is safe and easy to use.
Participants will:
* Receive either standard of care or standard of care plus electrical muscle stimulation of the thigh muscles * Have their muscle strength checked during the study * Complete a survey three months after ICU discharge to check on their recovery
Admitted to ER or ICU within the previous 48 hours
APACHE II score ≥ 13
Meets the criteria for sepsis or severe sepsis
Baseline Clinical Frailty Scale (CFS) ≤ 4
Anticipated transfer to an ICU not participating in this study
Expected length of ICU stay < 48 hours
Myopathies (e.g. congenital)
Acquired myopathies with CK levels 5-times above the upper limit of normal
Health Discovery Labs
Lead sponsor
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Collaborator
Mayo Clinic
Collaborator
Ascension Health
Collaborator
University of Texas at Austin
Collaborator