About this trial
The main goal of this study is to gain a thorough understanding, which specific factors drive the unhealthy sequelae of obesity. Therefore, the investigators want to understand:
1. What distinguishes obese persons without metabolic diseases from those with medical diseases in a cross-sectional comparison? 2. Which factors drive the conversions from metabolically healthy obesity into a metabolically unhealthy obesity in a longitudinal approach?
Eligibility criteria
Qualifiers
Signed Informed Consent Form
Age between 18 and 60 years
BMI 30-50 kg/m2
Knowledge of German, which requires sufficient written and allow oral patient education
Disqualifiers
Pregnancy
Medication and / or pathologies that prevent a safe execution of the fat tissue biopsies
History of or planned bariatric operation
Medical conditions that prevent examinations and testing (e.g. symptomatic cardiovascular diseases)
Trial design
Treatments tested in this trial
- Not listed