Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentro Cardiologico Monzino

About this trial

This is a prospective, observational, multicenter study aimed at characterizing tricuspid valve remodeling in patients with atrial fibrillation (AF) without significant tricuspid regurgitation (TR), in relation to AF burden progression.

Eligibility criteria

Qualifiers

Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset.

all consecutive patients with structurally normal hearts and no history of AF or;

moderate atrial functional tricuspid regurgitation and AF, in the absence of significant left-sided valvular disease or prior valvular surgery.

Disqualifiers

Moderate or greater TR assessed using a multiparametric approach;

Arrhythmias other than AF;

Prior AF ablations;

Rapid ventricular response (average HR >110 bpm) during baseline TTE;

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

66 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Centro Cardiologico Monzino

Lead sponsor

Istituto Clinico Humanitas

Collaborator