Natural History of Coronary Atherosclerosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorChina National Center for Cardiovascular Diseases

About this trial

The present study sought to explore the predictive value of radial wall strain (RWS, derived solely from angiograms) for coronary artery lesion progression compared with lesion vulnerability assessed by optical coherence tomography (OCT). The lesion progression at 1 year was defined as an increase of ≥20% in diameter stenosis based on quantitative coronary angiography (QCA) evaluation.

Eligibility criteria

Qualifiers

Age ≥18 years

Acute myocardial infarction ≤ 45 days

Planned coronary angiography examination or potential interventional treatment

The presence of at least 1 non-flow-restricting lesion (visually estimated diameter stenosis: 30%-80%; QFR > 0.80) in any non-infarct related artery with RVD ≥2.5 mm by visual assessment

Disqualifiers

Cardiogenic shock

Pregnant or woman of child-bearing potential

Life expectancy less than 1 year for non-cardiac causes

Unable to tolerate contrast agents or anticoagulant/antiplatelet therapy

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed