NBI Combined With MRI to Guide CTV Optimization in Eccentric Nasopharyngeal Carcinoma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChongqing University Cancer Hospital
About this trial
This is a prospective, single-center clinical trial in eccentric nasopharyngeal carcinoma (NPC) patients. The aim of this study is to evaluate the efficacy and safety of NBI combined with MRI-guided optimized CTV compared with conventional CTV, and to compare the radiotherapy-related adverse events and quality of life between the two groups.
Eligibility criteria
Qualifiers
Males and females ≥18 years of age;
ECOG Performance Status 0,1 or 2;
Pathologically diagnosed as nasopharyngeal carcinoma;
Pretreatment nasopharynx and neck MRI imaging;
Disqualifiers
Patients who did not successfully undergo all three examinations (MRI, NBI, and endoscopic biopsy);
Other rare pathological types, such as adenocarcinoma;
Patients with tumor invasion of the clivus;
Patients whose contralateral retropharyngeal lymph nodes met the diagnostic criteria;
Trial design
Treatments tested in this trial
- CTV optimized IMRT
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov