NC Testing in LC & POTS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Calgary
About this trial
Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or "Long COVID") experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive function in patients with POTS and Long COVID compared to placebo (50 mL of saline).
Eligibility criteria
Qualifiers
Patients with diagnosis of Long COVID
SARS-COV2 test positive
Symptoms > 12 weeks post COVID
Subjective complaint of 'brain fog" or cognitive dysfunction
Disqualifiers
Patients with overt causes for POTS (e.g., dehydration, prolonged bed rest)
An inability to safely withdraw from medicine(s) that could make test interpretation difficult and impossible.
Other factors which are in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies or an unpredictable schedule.
Unable to give an informed consent.
Trial design
Treatments tested in this trial
- IV normal saline (999 mL infusion)
- IV normal saline (50 mL infusion)
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov