NENCA Study on Neurological Complications of Long COVID-19 in Children and Adolescents; Neurophysiological, Electroencephalographic and Neuroradiological Investigation

ConditionLong Covid-19
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-16
SponsorAzienda Ospedaliero, Universitaria Pisana

About this trial

The study seeks to investigate the neurological effects caused by Covid-19 in children and adolescents in the 6-16 age group. To do this, neuropsychological scales, an EEG and an MRI were used.

Eligibility criteria

Qualifiers

Age between 6 years and 16 years and 11 months

Symptomatology compatible with long neurological COVID, specifically: persistence or appearance of new neurological signs/symptoms (e.g. fatigue, headache, sleep disturbance, cognitive dysfunction, memory difficulties, emotional or mood disorders, vertigo cognitive dysfunction, memory difficulties, emotional or mood disorders, dizziness, dysautonomia, movement disorders movement disorders, ataxia, tremor, epilepsy, muscle weakness, myalgia, hyposmia, hypogeusia hearing loss or tinnitus and/or sensorimotor deficits such as hypoesthesia, dysesthesia) after three months after established SARS-CoV-2 infection, as well as persistence of these symptoms for at least two months, in the absence of a clear aetiology.

Signature of the appropriate Informed Consent by caregiver(s) and patient(s)

Disqualifiers

Poor knowledge of the Italian language or other limitation of verbal communication that compromises the subject's ability to perform neuropsychological tests

Need for sedation to perform brain MRI 7 Tesla

Neurological or neuropsychiatric disorder diagnosed prior to COVID-19 diagnosis

Caregiver's failure to sign consent

Trial design

Treatments tested in this trial

  • Psychological tests, EEG, Magnetic Resonance

Treatment groups

100 Participants
are divided into 1 treatment group