About this trial
Neoadjuvant radiotherapy(NART) followed by mastectomy and immediate DIEP flap reconstruction is feasible and technically safe. However, reports of NACT followed immediate implant-based breast reconstruction are rare. Some studies have shown that NART followed immediate implant-based breast reconstruction seems feasible and can be safely attempted. It's well known that radiotherapy after implant-based breast reconstruction have negative effects on implant and cosmetic results. So, investigators conducted a polit study to learn about acute post-surgical complications following skin-sparing mastectomy and immediate implant-based breast reconstruction after NART.
Eligibility criteria
Qualifiers
require mastectomy for any reason
a known indication for (adjuvant) radiotherapy
require implant-based breast reconstruction
Disqualifiers
Inability to give informed consent
MDT unable to make recommendation for radiotherapy based on pre-operative histopathological and imaging findings
Previous history of breast cancer or another malignancy for which radiotherapy of the breast or axilla
Pregnant or lactating
Trial design
Treatments tested in this trial
- Neoadjuvant radiotherapy