Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorHubei Cancer Hospital

About this trial

Neoadjuvant radiotherapy(NART) followed by mastectomy and immediate DIEP flap reconstruction is feasible and technically safe. However, reports of NACT followed immediate implant-based breast reconstruction are rare. Some studies have shown that NART followed immediate implant-based breast reconstruction seems feasible and can be safely attempted. It's well known that radiotherapy after implant-based breast reconstruction have negative effects on implant and cosmetic results. So, investigators conducted a polit study to learn about acute post-surgical complications following skin-sparing mastectomy and immediate implant-based breast reconstruction after NART.

Eligibility criteria

Qualifiers

require mastectomy for any reason

a known indication for (adjuvant) radiotherapy

require implant-based breast reconstruction

Disqualifiers

Inability to give informed consent

MDT unable to make recommendation for radiotherapy based on pre-operative histopathological and imaging findings

Previous history of breast cancer or another malignancy for which radiotherapy of the breast or axilla

Pregnant or lactating

Trial design

Treatments tested in this trial

  • Neoadjuvant radiotherapy

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators