Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-5
SponsorAlexandria University
About this trial
The aim of this study is to determine the value of Pentoxifylline for nephroprotection in these neonates with perinatal asphyxia, using cystatin C, regional oxygenation measured near infrared spectroscopy and renal Doppler sonography.
Eligibility criteria
Qualifiers
Apgar score of less than or equal to 5 at 10 minutes.
ongoing resuscitation at 10 minutes.
pH less than 7.14 or a base deficit worse than or equal to minus 12 mmol/L on cord/arterial/venous/capillary blood gas obtained within 60 minutes of birth.
Evidence of moderate to severe encephalopathy using Sarnat staging score.(14)
Disqualifiers
None
Trial design
Treatments tested in this trial
- Pentoxifylline
- placebo distilled water
Treatment groups
30 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov