Nerve Transfer to Improve Function in High Level Tetraplegia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorWashington University School of Medicine
About this trial
The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.
Participants will:
* undergo standard of care pre- and post-op testing and study exams * complete pre- and post-questionnaires * undergo standard of care nerve transfer surgeries * follow-up with surgeon at 6/12/18/24/36 and potentially at 48 months * attend therapy at local therapist for up to 2 years postop.
Eligibility criteria
Qualifiers
18-80 years of age
High cervical SCI (motor level C1-C4)
Motor complete SCI AIS grade A-B
Plateaued spontaneous recovery for at least 6 months of non-operative therapy
Disqualifiers
Active infection at the operative site or systemic infection
Any return or ongoing recovery of distal motor function
Significant joint contractures and/or limitations in passive range of motion in the arm
Mentally or physically compromised making it impossible to complete study activities
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Washington University School of Medicine
Lead sponsor
University of Michigan
Collaborator
The Methodist Hospital Research Institute
Collaborator
University of Pennsylvania
Collaborator
University of Utah
Collaborator
Stanford University
Collaborator
University of Miami
Collaborator
Johns Hopkins University
Collaborator
University of Alberta
Collaborator
Wake Forest University Health Sciences
Collaborator
Congressionally Directed Medical Research Programs
Collaborator
Source ClinicalTrials.gov