About this trial
The purpose of this study is to see if stimulation of the brain can improve memory. The investigators will use a device called transcranial magnetic stimulation that can stimulate and activate a specific part of the brain that is important for memory. The study will enroll MCI subjects and subjects with subjective memory complaints who will be randomly assigned to receive active or sham brain stimulation. 'Blinded' or 'sham-controlled' means that the subject will not know whether the treatment they receive is the active treatment or the non-active stimulation. In the 'sham' condition, the stimulator will turn on but will not actually be stimulating the target brain region.
Eligibility criteria
Qualifiers
Agreement to participate in the study
55-100 years of age
Right-handedness
In good general health
Disqualifiers
Unwilling or unable to provide informed consent
Diagnosis of dementia
Active major medical, psychiatric, or neurologic disorder associated with neurocognitive impairment
History of alcohol or substance abuse
Trial design
Treatments tested in this trial
- Active Theta Burst Stimulation
- Sham Theta Burst Stimulation
Treatment groups
Sponsors and collaborators
University of California, Los Angeles
Lead sponsor
National Institute on Aging (NIA)
Collaborator