Neural Control of Kidney Blood Flow During Exercise in African American Adults

ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorUniversity of Massachusetts, Boston

About this trial

The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are:

* Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults?

During two visits in the research lab, participants will:

* Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test

Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.

Eligibility criteria

Qualifiers

Self-report as either African American or White racial identity

Born in United States

Both biological parents identify as same racial identity as participant

Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)

Disqualifiers

Hispanic or Latino

Females who are pregnant or lactating

Cardiovascular or renal disease

Hypertension (blood pressure of more than or equal to 130/80 mmHg)

Trial design

Treatments tested in this trial

  • Acute exercise
  • Cold pressor test
  • Mental stress test

Treatment groups

32 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Massachusetts, Boston

Lead sponsor

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator