About this trial
The goal of this clinical trials is to learn if healthy young African American (AA) adults have a larger change in their kidney blood flow during exercise compared to White (W) adults. The main questions that this study aims to answer are:
* Do healthy young AA adults have a larger decrease in kidney blood flow during exercise compared to W adults? * Do healthy young AA adults have a larger decrease in kidney blood flow during other types of stress compared to W adults?
During two visits in the research lab, participants will:
* Perform a fitness test * Perform cycling exercise while lying down * Undergo a cold hand test * Perform a mental math test
Completing this clinical trial will help researchers to understand more about why many AA adults have heart and kidney problems, so future research can study ways to reduce the number of AA adults who have these health issues.
Eligibility criteria
Qualifiers
Self-report as either African American or White racial identity
Born in United States
Both biological parents identify as same racial identity as participant
Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
Disqualifiers
Hispanic or Latino
Females who are pregnant or lactating
Cardiovascular or renal disease
Hypertension (blood pressure of more than or equal to 130/80 mmHg)
Trial design
Treatments tested in this trial
- Acute exercise
- Cold pressor test
- Mental stress test
Treatment groups
Sponsors and collaborators
University of Massachusetts, Boston
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator