Neural Correlates of Autistic Individuals With Anorexia Nervosa

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age25-45
SponsorUniversity of Aberdeen

About this trial

Masking is a behaviour or strategy used by many Autistic people to appear non-Autistic and blend in with a neurotypical society. The goal of this observational study is to understand the relationship between masking, anorexia nervosa symptoms and brain structure in Autistic people. The main questions this study aims to answer are:

* Do Autistic individuals with anorexia nervosa show differences in structure or function of the brain relation to Autistic individuals without anorexia nervosa? * Do Autistic individuals with anorexia nervosa display higher levels of masking than Autistic individuals without anorexia nervosa? * Are there indeed relationships between levels of masking, anorexia nervosa symptoms and brain structure in Autistic people?

Researchers will compare Autistic people without anorexia nervosa to Autistic people with anorexia nervosa to see if there are differences between groups. Participants will:

* Complete a series of questionnaires focused on eating disorder symptoms, autistic traits, autistic masking and psychological well-being * Undergo an MRI scan at the Aberdeen Royal Infirmary

Eligibility criteria

Qualifiers

Be aged 25-45 years

Be Autistic (clinically diagnosed and/or have an Autism Quotient (AQ-10) score of ≥6)

Be able to provide informed consent for the study

Be able to read, understand and respond to questionnaires in English

Disqualifiers

Are aged <25 or >45 years

Are not Autistic or not clinically diagnosed as Autistic and have an AQ-10 score of <6

Are diagnosed with an eating disorder other than anorexia nervosa

Have a history of brain injury (e.g., stroke)

Trial design

Treatments tested in this trial

  • Single Research Visit 3T MRI Research Scan
  • Demographic and Behavioural Questionnaires

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Aberdeen

Lead sponsor

NHS Grampian

Collaborator