Neural Correlates of Real World Spatial Navigation in Humans

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-70
SponsorDuke University

About this trial

The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.

Eligibility criteria

Qualifiers

12 years of age or older and has undergone RNS system placement

Willing to provide informed consent and participate the study

Ability to read and write English fluently

Disqualifiers

Unwilling to provide informed consent

Trial design

Treatments tested in this trial

  • Deep Brain Stimulation
  • Memory and spatial navigation tasks
  • Physiological Signals
  • Questionnaires and Assessments

Treatment groups

70 Participants
are divided into 1 treatment group

Sponsors and collaborators

Duke University

Lead sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator

National Institute of Mental Health (NIMH)

Collaborator