Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-22
SponsorUniversity of Michigan
About this trial
This study seeks to understand individual differences in personality, brain function, and behavior.
Study hypothesis:
\- A stronger sign-tracking bias will be associated with a bottom-up processing style characterized by less adaptive attentional- and impulse-control as well as hyperactive reward processing, whereas a stronger goal-tracking bias will be associated with a top-down processing style characterized by strong attentional- and impulse-control as well as normative reward processing.
Eligibility criteria
Qualifiers
18-22 years old at baseline
Right-handed
Medically/physically able to give informed consent
English-speaking
Disqualifiers
Acute or chronic medical or neurological illness (e.g., diabetes, epilepsy, migraine)
History of psychosis in self or first-degree relative
Current treatment for substance use disorder
Current or past 6-month treatment with centrally acting medications (not including attention deficit hyperactivity disorder (ADHD) medication)
Trial design
Treatments tested in this trial
- fMRI
- Questionnaires and surveys
- Behavioral tasks and eye tracking
Treatment groups
294 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Michigan
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov