About this trial
In the general population, 19.0-26.6 per 1000 cases of ankle instability have been reported, while in the athletic population, the rate is 11.3 per 1000. Ankle instability also predisposes individuals to recurrent instability, leading to persistent symptoms. After ankle injuries, temporary increases in afferent activity, along with long-term deficits in somatosensory information from ligaments, may cause central neuroplasticity that affects sensorimotor function. This central neuroplasticity can lead to permanent dysfunctions in the affected limb, thereby increasing the likelihood of developing and maintaining chronic ankle instability (CAI). In addition to the association between impaired balance and reduced proprioception with CAI, it has been reported that the central nervous system may fail to manage joint stress due to its inability to discern load on the ligaments.
Impaired neurocognition has been linked to decreased performance and higher rates of re-injury. Deficiencies in neuromuscular control, motor learning, or other neurocognitive components related to an individual's performance and safety may affect the ability to respond appropriately in a dynamic environment. Any deficiencies in these neurocognitive processes can hinder the successful completion of tasks.
The aim of this study is to comparatively examine the effects of neurocognitively enriched rehabilitation versus traditional rehabilitation on re-injury risk, balance, and proprioception in individuals with a history of ankle instability.
Eligibility criteria
Qualifiers
The documented unilateral ankle instability confirmed through clinical examinations (drawer test, talar tilt test) and MRI in cases requiring differential diagnosis.
A history of an initial ankle sprain occurring at least 6 months ago.
The presence of a recurrent sense of giving way that started at least 6 months ago and has been intermittently persistent.
Disqualifiers
Presence of a history of previous surgery in the lower extremity.
Identification of organic and non-organic lesions such as cartilage injuries, periarticular tendon tears, and impingement syndromes.
The existence of a fracture accompanying instability in the foot-ankle.
Presence of congenital deformities in the foot-ankle.
Trial design
Treatments tested in this trial
- Neurocognitive Enriched Exercise
- Multimodal Exercise
Treatment groups
Sponsors and collaborators
Istanbul University - Cerrahpasa
Lead sponsor
Bezmialem Vakif University
Collaborator
Acıbadem Atunizade Hospital
Collaborator