Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorTrustees of Princeton University

About this trial

This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.

Eligibility criteria

Qualifiers

Adults aged 18-50

No history of psychiatric disorders or neurological disorders affecting the central nervous system.

Are not currently taking psychoactive medication or drugs of abuse.

Must be eligible to enter an MRI (i.e., no permanent metal or medical implants)

Disqualifiers

Pregnancy (female participants)

Outside of age range

History of psychiatric or neurological disease

Currently taking psychoactive medication or drugs of abuse

Trial design

Treatments tested in this trial

  • Active Real-time fMRI Neurofeedback
  • Sham Real-time fMRI neurofeedback

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Trustees of Princeton University

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator