About this trial
This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.
Eligibility criteria
Qualifiers
Adults aged 18-50
No history of psychiatric disorders or neurological disorders affecting the central nervous system.
Are not currently taking psychoactive medication or drugs of abuse.
Must be eligible to enter an MRI (i.e., no permanent metal or medical implants)
Disqualifiers
Pregnancy (female participants)
Outside of age range
History of psychiatric or neurological disease
Currently taking psychoactive medication or drugs of abuse
Trial design
Treatments tested in this trial
- Active Real-time fMRI Neurofeedback
- Sham Real-time fMRI neurofeedback
Treatment groups
Sponsors and collaborators
Trustees of Princeton University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator