Neuroimaging Reveals Treatment-related Changes in DLD

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age48-71
SponsorUniversity of Cincinnati

About this trial

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.

Eligibility criteria

Qualifiers

ages 48-71 months

average nonverbal intelligence quotient (IQ)

enrolled in participating center

typically developing (receptive and expressive language, social, articulation, other)

Disqualifiers

receiving co-occurring speech-language or other intervention for communication

not MRI safe

special education placement of child based on ability or behavior

Trial design

Treatments tested in this trial

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Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Cincinnati

Lead sponsor

Children's Hospital Medical Center, Cincinnati

Collaborator

University of Toronto

Collaborator