This study aims to explore the impact of Animal Assisted Therapy (AAT) on brain signal complexity in patients with minimally conscious state (MCS) by analyzing electroencephalogram (EEG) entropy. MCS patients typically exhibit reduced brain entropy compared to healthy individuals, indicating lower brain complexity. The study will assess whether AAT can enhance this complexity, which is crucial for understanding consciousness levels. Entropy, a measure of randomness in brain activity, will be used to evaluate AAT's effectiveness. In addition, electrocardiography (ECG), electrodermal activity (EDA) and behavioral measurements will also be collected.
Inpatients in one of the study sites
Acquired brain injury resulting from either traumatic or non-traumatic events
Diagnosis of MCS defined by CRS-R according to the Aspen criteria (Giacino, 2005)
Informed consent as documented by signature by the patient's legal representative
Phobia or allergies to any of the involved animals
Medical contraindications: acute or chronic disease (e.g. chronic pain, hypertension, heart disease, renal disease, liver disease, diabetes)
Radical changes in medication (decision made with responsible physician)
University of Basel
Lead sponsor
Rehab Basel
Collaborator