Neuromodulation and Neurorehabilitation for mTBI
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNorthwestern University
About this trial
This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing training (APT) when combined with intermittent theta burst stimulation (iTBS), a type of repetitive transcranial magnetic stimulation and (ii) determine how APT + iTBS changes the neurocognitive system of attention in individuals with persistent attention deficits related to mTBI +/- PTSD.
Eligibility criteria
Qualifiers
At least 18 years of age and no older than 80 years of age
3 months post exposure to mTBI event
Have a history of mTBI with PTSD OR mTBI without PTSD as defined by formalized measures to classify mTBI based on the Symptom Attribution and Classification Algorithm (SACA) and the PTSD Module L of the SCID
Endorse at least moderate severity on at least one of the four cognitive complaints in the Neurobehavioral Symptom Inventory
Disqualifiers
Participating in another research study
Non-fluent in English (speaking and reading)
History of epilepsy pre-injury
Receiving antiepileptic treatment for documented active seizures in the past 6 months
Trial design
Treatments tested in this trial
- real iTBS
- real APT
- placebo APT
- placebo iTBS
Treatment groups
200 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov