Neuropathic Dental Pain & DBS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-80
SponsorUniversity of British Columbia
About this trial
This prospective observational study will evaluate pain outcomes in patients with neuropathic dental pain (Atypical Odontalgia/Phantom Tooth Pain) who undergo directional deep brain stimulation (DBS). Participants will complete validated pain, disability, quality-of-life, and mood assessments before surgery and following DBS programming. Directional stimulation will be applied to different thalamic targets to determine whether specific stimulation settings are associated with greater pain relief. The study aims to characterize changes in pain and quality of life following DBS and to identify the stimulation target associated with the greatest reduction in neuropathic dental pain.
Eligibility criteria
Qualifiers
Age 19 to 80 years.
Diagnosis of Atypical Odontalgia (AO) (also known as neuropathic dental pain).
Receiving deep brain stimulation (DBS) treatment for AO due to inadequate response to conventional therapies, including: Pharmacological therapies, and/or Local anesthetics, corticosteroid injections, or nerve blocks.
Able and willing to provide informed consent.
Disqualifiers
Refusal or inability to provide informed consent.
Known major depression.
Acute psychosis.
Trial design
Treatments tested in this trial
- Directional Deep Brain Stimulation
Treatment groups
5 Participants
are divided into 5 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov