Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

ConditionsLung Injury Cardiopulmonary Bypass

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

AgeUp to 12

SponsorSophia Koutsogiannaki

About this trial

Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.

Eligibility criteria

Qualifiers

Are < 12months of age

Scheduled for cardiac surgical needing CPB

Preoperative SpO2 > 90%

Disqualifiers

Lack of parental (or legal guardian's) consent

Preoperative SpO2 < 90%

Preoperative oxygen therapy

Trial design

Treatments tested in this trial

Research study

Treatment groups

56 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Sophia Koutsogiannaki

Lead sponsor

Boston Children's Hospital

Sponsor institution

Source ClinicalTrials.gov