New Treatment for Nocturnal Enuresis in Children
ConditionNocturnal Enuresis in Children
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-18
SponsorSohag University
About this trial
The aim of the study is to evaluate the role of sulbutiamine in treatment of monosymptomatic nocturnal enuresis in children by using it alone or as a combination therapy with tricyclic antidepressants (imipramine+sulbutiamine).
Eligibility criteria
Qualifiers
Age : 6 - 18 years old.
All children diagnosed by Primary monosymptomatic nocturnal enuresis in this age group.
Disqualifiers
Secondary nocturnal enuresis (child who has been continent for at least 6 months before the onset of bedwetting ).
congenital anomalies (Posterior urethral valve , ectopic ureter , ectopia vesica ,…)
history of previous lower urinary tract surgery (Multiple hypospadias surgeries ,…, )
neurogenic bladder (as underactive bladder ).and urge incontinence.
Trial design
Treatments tested in this trial
- Sulbutiamine
- Imipramine
Treatment groups
450 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov