Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorThe Cleveland Clinic
About this trial
To determine if nifedipine and enalapril will have better blood pressure control in the postpartum setting compared to nifedipine and labetalol.
Eligibility criteria
Qualifiers
Postpartum women aged 18 years or older
Clinical diagnosis of hypertensive disorder in pregnancy (gestational hypertension, chronic hypertension, preeclampsia with or without severe features)
Taking Nifedipine 60 mg every 12 hours for blood pressure control
Persistently elevated blood pressure at/above 140/90 mmHg in a 24-hour time period or have one or more severe range blood pressure at/above 160/110 mmHg requiring a second antihypertensive medication
Disqualifiers
Taking ≥2 antihypertensive agents during pregnancy
Heart block
Heart rate <60 or >120 beats per minute
Heart failure
Trial design
Treatments tested in this trial
- Nifedipine and Enalapril
- Nifedipine and Labetalol
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov