Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMassachusetts General Hospital

About this trial

The goal of this observational study is to understand if angiographic cerebral vasospasm (CV) can be predicted by levels of nitric oxide (NO) consumption in patients with aneurysmal subarachnoid hemorrhage (SAH). To reach this goal, the investigators will compare NO consumption levels in SAH and non-SAH patients. NO consumption levels will be analyzed from samples of participants' cerebral spinal fluid (CSF).

Eligibility criteria

Qualifiers

Adult

patient with SAH and with an external ventricular drainage (EVD) placed within 24 hours after the onset of the hemorrhage

Disqualifiers

pregnancy

pre-existing neurological comorbidities

coagulation disorders

anemia

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

40 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Massachusetts General Hospital

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Collaborator