NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorADIR Association
About this trial
The objectives of this study are to compare the physiological consequences of high-flow oxygen therapy and noninvasive mechanical ventilation on ventilation, respiratory work and hemodynamics during acute respiratory failure in diffuse interstitial pneumonia.
Eligibility criteria
Qualifiers
Age > 18 yrs
Hospitalization in intensive care unit
Acute exacerbation of a previously/presently documented diffuse (fibrotic) interstitial lung disease
Dyspnea majoration since at least 1 month
Disqualifiers
Contraindication to noninvasive ventilation or high-flow oxygen therapy
Immediate indication to endotracheal intubation or hemodynamic assistance
Body mass index > 40
Presence of a pacemaker or an implantable defibrillator
Trial design
Treatments tested in this trial
- Noninvasive mechanical ventilation
- Nasal high-flow oxygen therapy
- Continuous positive airway pressure
Treatment groups
18 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Sponsors and collaborators
Source ClinicalTrials.gov