About this trial
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.
Eligibility criteria
Qualifiers
willing and capable to give informed consent for the participation in the study after it has been thoroughly explained
able and willing to comply with all study requirements
an informed consent form was signed
able to read, write, and communicate in English
Disqualifiers
major psychiatric co-morbidity including major depressive disorder, schizophrenia or psychosis
blindness or other disabilities that prevent task performance
contraindications to tES, as recorded on a standardized screening questionnaire, which include a reported seizure within the past two years, use of neuroactive drugs, self-reported presence of specific implanted medical devices (e.g., deep brain stimulator, medication infusion pump, cochlear implant, etc.)
the presence of any active dermatological condition, such as eczema, on the scalp a score of 18 or less on the Montreal Cognitive Assessment (MoCA) during the in-person screen
Trial design
Treatments tested in this trial
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)
- Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham)
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham)
- Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (active)
Treatment groups
Sponsors and collaborators
Hebrew SeniorLife
Lead sponsor
BrightFocus Foundation
Collaborator
National Institute on Aging (NIA)
Collaborator