Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorMidwestern University

About this trial

The goal of this randomized controlled trial is to test the effectiveness of non-invasive brain stimulation in treating adults with symptomatic convergence insufficiency compared to vergence/accommodative therapy. The main questions it aims to answer are:

1. Can non-invasive brain stimulation shorten the treatment time of office-based vergence/accommodative therapy for convergence insufficiency? 2. Is non-invasive brain stimulation alone just as effective as office-based vergence/accommodative therapy in treating convergence insufficiency?

The investigators hypothesize that non-invasive brain stimulation will shorten the treatment time from 12 weeks to 8 weeks of office-based vergence/accommodative therapy and that non-invasive brain stimulation alone would be equally effective as office-based vergence/accommodative therapy in improving symptomatic convergence insufficiency.

Participants will be randomized into one of three treatment groups:

1. Non-invasive brain stimulation with office-based vergence/accommodative therapy. 2. Sham stimulation with office-based vergence/accommodative therapy. 3. Non-invasive brain stimulation only.

Researchers will compare baseline measurements of near point of convergence (NPC) and positive fusional vergence (PFV) to post-treatment measurements for each group.

Eligibility criteria

Qualifiers

Best-corrected visual acuity of > 20/25 in each eye at distance and near

Exophoria at near at least 4∆ greater than at far

Receded near point of convergence of > 6 cm break

Insufficient positive fusional vergence at near (< 15∆ base-out blur or break)

Disqualifiers

Previously treated for convergence insufficiency with home- or office-based vergence/accommodative therapy

Amblyopia (> 2-line difference in best-corrected visual acuity between the two eyes)

Constant strabismus

History of strabismus surgery

Trial design

Treatments tested in this trial

  • Anodal-Transcranial Direct Current Stimulation
  • Office-Based Vergence/Accommodative Therapy
  • Sham Transcranial Direct Current Stimulation

Treatment groups

150 Participants
are divided into 3 treatment groups

Sponsors and collaborators