Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Erlangen-Nürnberg Medical School

About this trial

In this study, the condition of the kidney transplant in adults is to be assessed non-invasively using Multispectral Optoacoustic Tomography and Ultrasound Localization Microscopy (ULM). ULM imaging can be performed in a 2-dimensional and a 3-dimensional way (2D and 3D ULM). Therefore, "ULM" in the following texts and measures will refer to 2D and 3D ULM.

New, non-invasive markers that allow conclusions to be drawn about the condition of the transplant should reduce the need for invasive diagnostic procedures in the future.

Eligibility criteria

Qualifiers

kidney transplant

indication for biopsy set in clinical routine

minimum 18 years of age

written consent

Disqualifiers

allergy against contrast agents/ SonoVue

tatoos in examined areas

contraindication against SonoVue

pregnant women

Trial design

Treatments tested in this trial

  • ULM and MSOT

Treatment groups

10 Participants
are divided into 1 treatment group