Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorOslo University Hospital
About this trial
Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.
Eligibility criteria
Qualifiers
Sinus rhythm.
New York Heart Association class II / III heart failure on diagnosis and on optimal medical therapy.
Left bundle branch block.
QRS duration ≥ 130 ms.
Disqualifiers
Age < 18 years and > 80 years;
Ongoing atrial fibrillation;
Complete atrioventricular block
Trial design
Treatments tested in this trial
- Cardiac Resynchronization Therapy (CRT)
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Oslo University Hospital
Lead sponsor
South-Eastern Norway Regional Health Authority
Collaborator
Norwegian Health Association
Collaborator
Source ClinicalTrials.gov