Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKuopio University Hospital

About this trial

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Eligibility criteria

Qualifiers

Mild Cognitive Impairment due to Alzheimer's disease

Dementia with Lewy Bodies

Frontotemporal dementia

Idiopathic normal pressure hydrocephalus (iNPH)

Disqualifiers

History of seizures

Pregnancy

Metal implants in the head (except dental fillings)

Electronic implants (i.e. pace-maker, implanted medical pump)

Trial design

Treatments tested in this trial

  • Gamma tACS (40 Hz) over the superior parietal cortex

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators