Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 18
SponsorAssiut University
About this trial
The goal of this observational study:
* To evaluate the diagnostic accuracy of non-invasive markers in predicting the presence and grading of esophageal varices in children with portal hypertension. * To correlate these non-invasive markers with the severity of portal hypertension and the grade of esophageal varices to identify patients at high risk of bleeding. * To propose a defined protocol for screening esophageal varices in those children.
Eligibility criteria
Qualifiers
Patients aged less than 18 years diagnosed with portal hypertension either due to hepatic or extrahepatic causes
Disqualifiers
Active variceal bleeding at presentation (hemodynamic instability affects platelet/spleen parameters).
Previous history of variceal bleeding or endoscopic intervention (band ligation/sclerotherapy).
Prior surgical portosystemic shunts or Transjugular Intrahepatic Portosystemic Shunt (TIPS).
Current use of vasoactive drugs for primary prophylaxis (e.g., Non-selective beta-blockers).
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Locations
Sponsors and collaborators
Source ClinicalTrials.gov