About this trial
This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of individuals with spinal cord injury (SCI).
Eligibility criteria
Qualifiers
Resident of British Columbia, Canada with active provincial medical services plan.
Male or female, 19-60 years of age.
Chronic traumatic SCI (non-progressive, with complete motor paralysis) at or above the T6 spinal segment.
>1-year post injury, at least 6 months from any spinal surgery.
Disqualifiers
Ventilator dependent.
Signs of lower motor neuron damage (i.e. concomitant conus medullaris/cauda equina injury).
Severe anemia or hypovolemia as measured by hematocrit via blood test in the last six months.
History of cardiovascular, respiratory, bladder, or renal disease unrelated to SCI or presence of hydronephrosis or presence of obstructive renal stones.
Trial design
Treatments tested in this trial
- TESCoN or SCONE device - Thoracic stimulation
- TESCoN or SCONE device - Lumbosacral stimulation
Treatment groups
Sponsors and collaborators
University of British Columbia
Lead sponsor
United States Department of Defense
Collaborator
Congressionally Directed Medical Research Programs
Collaborator