Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-60
SponsorUniversity of British Columbia

About this trial

This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of individuals with spinal cord injury (SCI).

Eligibility criteria

Qualifiers

Resident of British Columbia, Canada with active provincial medical services plan.

Male or female, 19-60 years of age.

Chronic traumatic SCI (non-progressive, with complete motor paralysis) at or above the T6 spinal segment.

>1-year post injury, at least 6 months from any spinal surgery.

Disqualifiers

Ventilator dependent.

Signs of lower motor neuron damage (i.e. concomitant conus medullaris/cauda equina injury).

Severe anemia or hypovolemia as measured by hematocrit via blood test in the last six months.

History of cardiovascular, respiratory, bladder, or renal disease unrelated to SCI or presence of hydronephrosis or presence of obstructive renal stones.

Trial design

Treatments tested in this trial

  • TESCoN or SCONE device - Thoracic stimulation
  • TESCoN or SCONE device - Lumbosacral stimulation

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of British Columbia

Lead sponsor

United States Department of Defense

Collaborator

Congressionally Directed Medical Research Programs

Collaborator