Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorOndokuz Mayıs University

About this trial

The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment.

The main questions this study aims to answer are:

Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study.

All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour.

Participants will:

Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.

Eligibility criteria

Qualifiers

Willingness to participate in the study and provide written informed consent

Age 18 years or older

No periodontal treatment within the past 6 months

No use of local or systemic antibiotics within the past 3 months

Disqualifiers

Unwillingness to participate in the study or to provide informed consent

Age under 18 years

Use of local or systemic antibiotics for the treatment of widespread infection

within the past 3 months

Trial design

Treatments tested in this trial

  • Non-surgical periodontal therapy (scaling and root planing)
  • Non-surgical periodontal therapy (Professional dental cleaning)

Treatment groups

60 Participants
are divided into 3 treatment groups

Sponsors and collaborators