Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorVanderbilt University

About this trial

The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study will first establish the efficacy of a novel, noninvasive stimulation protocol on reading behavior and brain metrics; then will determine how stimulation-induced effects interact with baseline reading comprehension ability; and lastly, will identify whether stimulation-induced effects are more clinically-beneficial than canonical behavioral interventions. Results may change the foundation for how we treat low adult literacy, and have the potential for wider reaching impacts on non-invasive stimulation protocols for other clinical disorders.

Eligibility criteria

Qualifiers

None

Disqualifiers

previous diagnosis of Intellectual Disability;

known uncorrectable visual impairment;

documented hearing impairment greater than or equal to a 25 dB loss;

medical contraindication to MRI procedures (e.g., metal devices);

Trial design

Treatments tested in this trial

  • Sham intervention
  • RLN real non-invasive brain stimulation intervention
  • RLN and CCN real non-invasive brain stimulation intervention

Treatment groups

100 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Vanderbilt University

Lead sponsor

National Institutes of Health (NIH)

Collaborator