About this trial
Echocardiography is the main method of bedside examination of neonatal cardiac morphology, which can timely diagnose congenital heart disease and quantitatively assess its severity, but the diagnosis and evaluation process depends on the normal range of neonatal echocardiography.At present, there have been normal reference standards for echocardiography in children and adults at home and abroad, but there is no uniform standard for echocardiographic parameters in newborns, especially premature infants.This study intends to carry out a national multicenter, prospective, observational study to establish the reference range of echocardiography at different time periods after birth in newborns, and stratified according to gestational age, birth weight and gender, to conduct a more accurate hemodynamic assessment of clinically critically ill newborns and guide the treatment of critically ill newborns in real time.
Eligibility criteria
Qualifiers
Outpatient or inpatient neonate
Gestational age > 30weeks and birthweight > 1250 grams
Appropriate for gestational age
Without perinatal asphyxia
Disqualifiers
specialist cardiac ultrasound suggests congenital heart disease;
PDA with hemodynamic abnormalities, defined as: PDA > 1.5 mm (left-to-right shunt) and left atrial diameter/aortic root > 1.5 or the need for the use of inotropes;
invasive mechanical ventilation therapy,
non-invasive mechanical ventilation with FiO2 >0.3
Trial design
Treatments tested in this trial
Treatment groups
Sponsors and collaborators
Children's Hospital of Chongqing Medical University
Lead sponsor
Shanxi Provincial Maternity and Children's Hospital
Collaborator
Inner Mongolia Maternal and Child Health Care Hospital
Collaborator
Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region
Collaborator
Ningxia Medical University
Collaborator