Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optical Coherence Tomography Angiography

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

Optical coherence tomography angiography (OCT-A) is a determinant progress to study retinal and choroidal vasculature without using a dye injection. OCT-A yields interesting results in different pathologies such as diabetes mellitus, age-related macular degeneration, hypertension blood pressure, particularly by affecting vascular density. Normative database are necessary to compare OCT-A parameters between patients and controls. However, OCT-A devices from different manufactures may give different values for the same subject. It seems to be obvious that each OCT-A device should have its own normative database. In the literature, OCT-A normative databases are developing using different types of devices, but none is available for Heidelberg OCT-A in Caucasians. The purpose of this project is to create a normative database of retinal microvascularisation using Spectralis Heidelberg optical coherence tomography angiography (OCT-A) ® in normal controls.

Eligibility criteria

Qualifiers

Voluntary adult subjects or legal representative consenting for minor or subjects under protection

Intra ocular pression ≤ 21mmHg

Spherical refraction comprised between - 6 D and +6 D and/or axial length between 21 and 26mm

Patient affiliated to social security system

Disqualifiers

Ocular diseases: glaucoma, retinal diseases as diabetic retinopathy, age-related macular degeneration, amblyopia, optic neuropathy

Diabetes mellitus

Uncontrolled hypertension blood pressure (> 140/90)

Recent ocular surgery (< 6 months)

Trial design

Treatments tested in this trial

  • Optical coherence tomography angiography
  • ophthalmological exam

Treatment groups

200 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Hospitalier Universitaire, Amiens

Lead sponsor

GHPSO de Creil

Collaborator

Hôpital Saint Vincent de Paul, Lille

Collaborator