NSCLC Liquid Biopsies and Exhaled VOC

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSt. Joseph's Healthcare Hamilton

About this trial

The objective of the study is to determine the feasibility of recruiting participants and using sputum, Bronchoalveolar lavage (BAL) and exhaled Volatile Organic Compounds (VOC) in addition to blood, as biological samples for detecting mutations in extracted cell-free DNA in non-small cell lung cancer (NSCLC) patients, before and after surgery, and any recurrence within a 24-month postoperative follow-up period.

This is a pilot feasibility study, proposed as a 24-month prospective, single-center, non-interventional, observational trial with NSCLC-adenocarcinoma patients indicated for resection surgery with curative intent.

Eligibility criteria

Qualifiers

Patient must be at least 18 years of age

Patient must be able to provide consent

Patients undergoing surgical resection with curative intent for non-small cell lung cancer at St. Joseph's Healthcare Hamilton and Firestone Institute for Respiratory Health.

Disqualifiers

Resection done with non-curative intent or metastatic disease

other malignancies

Patients with previously treated malignancy less than 5 years prior to current resection (not including skin cancer).

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed