Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age19+
SponsorYonsei University

About this trial

Prostate cancer is the 2nd most common cancer in men worldwide. Based on the results of several recent clinical trials, systemic treatments including hormone inhibitors, docetaxel, cabazitaxel, and PARP inhibitors are being used as standard treatment for patients with metastatic castration-resistant prostate cancer. However, there is insufficient research on salvage therapy for patients with metastatic castration-resistant prostate cancer who have failed standard treatment. In this study, the investigators will evaluate the effectiveness and safety of ifosfamide in castration-resistant prostate cancer by analyzing the treatment outcomes of patients who received ifosfamide/mesna treatment as salvage therapy.

Eligibility criteria

Qualifiers

19 years and older adult male

Patients with histologically confirmed prostate cancer

Castration-resistant prostate cancer

ECOG 2 or less

Disqualifiers

Patients with other primary cancers diagnosed within 3 years other than prostate cancer

Patients with a history of organ transplantation

Hormone sensitive prostate cancer

ECOG 3 or higher

Trial design

Treatments tested in this trial

  • Ifosfamide/mesna

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators