Observational Study for SIR-Spheres Therapy for the Treatment of Unresectable Metastatic Liver Tumors From Primary Colorectal Cancer

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorGrandPharma (China) Co., Ltd.

About this trial

This real-world study tries to collect data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable liver metastases from Metastatic Liver Tumors From Primary Colorectal Cancer (mCRC) refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-Spheres in China.

Eligibility criteria

Qualifiers

Obtained informed consent for patients to be follow-up prospectively

Age≥18 years old

Histologically or pathologically confirmed diagnosis of unresectable metastatic liver tumors from primary colorectal cancer and failed standard of care

Received SIR-Spheres®

Disqualifiers

Special contraindications from package insert, which includes

Markedly abnormal liver function tests, such as total bilirubin > 2.0 mg/dL or albumin <3.0 g/dL

Portal vein thrombosis in the main trunk

Disseminated extrahepatic disease

Trial design

Treatments tested in this trial

  • Resin microspheres containing yttrium-90 (Y-90)

Treatment groups

No treatment groups listed

Sponsors and collaborators