OCT in Diagnosis of Irregular Corneas
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age14-85
SponsorOregon Health and Science University
About this trial
This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions.
The primary goal will be achieved by using optical coherence tomography (OCT) to:
1. Develop an OCT-based system to classify and evaluate corneal-shape irregularities. 2. Develop OCT metrics for more sensitive detection of keratoconus progression. 3. Develop OCT-and-topography guided phototherapeutic keratectomy (PTK) for irregular corneas.
Eligibility criteria
Qualifiers
CDVA ≥ 20/25 in the better eye; and both of the following in the worse eye
Topography characteristic of keratoconus or pellucid marginal degeneration
Contact lens use; and
Topography irregularities
Disqualifiers
Inability to give informed consent.
Inability to maintain fixation for OCT imaging.
Inability to commit to required study visits.
Eyes with concurrent cataract, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery.
Trial design
Treatments tested in this trial
- Optical Coherence Tomography
Treatment groups
445 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov