Ocular Microbiome and Immune System in Dry Eyes
ConditionDry Eye Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorInsel Gruppe AG, University Hospital Bern
About this trial
The primary objectives of this study are the characterization of the ocular microbiome as well as of the local immune system in participants with and without dry eye disease. Secondary objectives are the identification of differences in the ocular microbiome as well as in the immune system between participants with and without dry eye disease to ultimately find associations between the ocular microbiome and the immune system in dry eye disease.
Eligibility criteria
Qualifiers
Willing to sign informed consent
18 years of age or older
Disqualifiers
Not willing or able to sign informed consent
Younger than 18 years
Recent (3 month) history of use of systemic and/or topical antibiotics
Usage of medical eye drops (Lacrycon and other moisturizing eye drops are allowed)
Trial design
Treatments tested in this trial
- Ocular microbiome
- Ocular immune system
Treatment groups
600 Participants
are divided into 2 treatment groupsSponsors and collaborators
Insel Gruppe AG, University Hospital Bern
Lead sponsor
Stiftung OPOS
Collaborator
Fondation Bertarelli
Collaborator
Source ClinicalTrials.gov