About this trial
The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences?
Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses.
Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.
Eligibility criteria
Qualifiers
Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report)
Fluent in English (self-report)
Right-handed (self-report)
Cognitively healthy (self report verified by score > 24 on Montreal Cognitive Assessment)
Disqualifiers
Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease)
Self-reported uncontrolled hypertension, diabetes, or thyroid disorder
Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form)
Self-reported difficulty lying still on one's back for 1-2 hours
Trial design
Treatments tested in this trial
- Memory decision type
Treatment groups
Sponsors and collaborators
Caitlin Bowman
Lead sponsor
University of Wisconsin, Milwaukee
Sponsor institution
National Institute on Aging (NIA)
Collaborator