Older Age and Generalization

ConditionAging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorCaitlin Bowman

About this trial

The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences?

Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses.

Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.

Eligibility criteria

Qualifiers

Either aged 18-30 years (young adults) or aged 65-80 years (older adults) (self-report)

Fluent in English (self-report)

Right-handed (self-report)

Cognitively healthy (self report verified by score > 24 on Montreal Cognitive Assessment)

Disqualifiers

Self-reported neurological disorder (e.g., Alzheimer's or Parkinson's disease)

Self-reported uncontrolled hypertension, diabetes, or thyroid disorder

Having conditions or devices that are unsafe for MRI (assessed via imaging center's MRI safety screening form)

Self-reported difficulty lying still on one's back for 1-2 hours

Trial design

Treatments tested in this trial

  • Memory decision type

Treatment groups

360 Participants
are divided into 1 treatment group

Sponsors and collaborators

Caitlin Bowman

Lead sponsor

University of Wisconsin, Milwaukee

Sponsor institution

National Institute on Aging (NIA)

Collaborator