Older People's Neurocognitive Recovery After Cardiac Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorKarolinska Institutet

About this trial

Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing, and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications. The purpose of this study is to measure older persons' postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives' experiences of it. We will include 220 participants ≥65 years of age undergoing planned cardiac surgery. Cognitive symptoms and signs and neurocognitive function will be assessed up to 6 months after surgery. Risk/affected factors such as delirium, functional status, recovery, depression, and healthcare-related quality of life, as well as close relative's experiences and burden, will be measured. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhancing knowledge about postoperative cognitive decline and recovery, and subsequently identifying what support needs to be implemented.

Eligibility criteria

Qualifiers

Scheduled for elective or urgent open-heart surgery or minimally invasive cardiac surgery

Resident in the area/region for the current thoracic clinic

Able to read and understand Swedish

Disqualifiers

Physical, mental, and cognitive difficulties that prevent the individual from completing the cognitive tests

Undergone surgery within the last 6 months

Trial design

Treatments tested in this trial

  • Elective or urgent cardiac surgery

Treatment groups

No treatment groups listed

Sponsors and collaborators

Karolinska Institutet

Lead sponsor

Sahlgrenska University Hospital

Collaborator