Olfactory Training As a Treatment for Olfactory Dysfunction Post COVID-19
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversité du Québec à Trois-Rivières
About this trial
Olfactory dysfunction is a defining symptom of COVID-19 infection. Studies have demonstrated improved olfaction in patients with post infectious olfactory dysfunction after an olfactory training (OT). The aim of this study is to assess the clinical outcomes of olfactory training (12 weeks) therapy in the treatment of persistent olfactory dysfunctions after COVID-19. Specially, we aim to compare the effectiveness of two different olfactory training (different odors).
A group will train themselves with 4 scents (rose, orange, clove and eucalyptus) and another group with 4 different scents (cheese, coffee, strawberries and lemon). Olfaction sensory evaluation will be performed by using different olfaction tests (Sniffin' Sticks and UPSIT) and complete questionnaires to assess olfactory perception and particularly parosmia and phantosmia.
Eligibility criteria
Qualifiers
Patient diagnosed positive for COVID-19 with persistent olfactory dysfunction
Willing and able to provide written informed consent
Understand and read the French language
Have an internet connection and a working email address
Disqualifiers
Anosmia and hyposmia pre-covid-19
Be known chronic rhinosinusitis with or without nasal polyposis
Have received radiotherapy or chemotherapy for Head and Neck Tumors
Have a diagnosis of Alzheimer's, Parkinson's, multiple sclerosis or any other neurodegenerative disease 5. Have a brain tumor or ENT diagnosis 6. History of naso-sinus surgery; 7. History of traumatic brain injury
Trial design
Treatments tested in this trial
- Smell training
Treatment groups
70 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov