Olfactory Training on Smell Dysfunction Patients in HK

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorPamela Youde Nethersole Eastern Hospital

About this trial

* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.

Eligibility criteria

Qualifiers

Olfactory dysfunction > 6 months and < 5 years

Disqualifiers

History of significant head injury (fracture, ICH)

History of brain surgery

History of nasal surgery

Active nasal disease

Trial design

Treatments tested in this trial

  • Olfactory Training
  • Control

Treatment groups

80 Participants
are divided into 2 treatment groups