The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an idea how well the person is doing.
Males or females 3 years of age and older
History of intestinal surgery other than G tube placement
Enrolled in a blinded investigational study at the time of the first study visit
Have esophageal stricture (<3mm)
Have other identifiable causes for eosinophilia (except Inflammatory Bowel Disease): infections, Gastrointestinal (GI) cancer, other GI inflammatory disease (e.g., Ulcerative Colitis or Crohn's Disease)
Children's Hospital Medical Center, Cincinnati
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
ORDR
Collaborator
National Center for Advancing Translational Sciences (NCATS)
Collaborator