Open Label Trial of Deceased Donor Livers Transplanted After DHOPE With eXVIVO LIVER Perfusion
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorXVIVO Perfusion
About this trial
The purpose of this clinical study is to confirm the safety and effectiveness of dual hypothermic oxygenated perfusion (DHOPE) using the Liver Assist to preserve deceased donor livers for transplantation.
Eligibility criteria
Qualifiers
Participant is able to provide informed consent and HIPAA authorization
Age ≥18 years
Participant is registered as an active first-time liver transplant candidate on the United Network for Organ Sharing (UNOS) waiting list for primary liver transplantation
Participant is willing to comply with the study requirements and procedures
Disqualifiers
Participant will undergo concurrent multi-organ transplantations (liver-kidney, liver-lung, etc.)
Participant is listed for liver transplantation due to fulminant liver failure (UNOS status 1A)
Participant is listed for a repeat liver transplantation (>1 graft)
Participant is pregnant
Trial design
Treatments tested in this trial
- dual hypothermic oxygenated perfusion (DHOPE)
Treatment groups
215 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov